The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.

The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.

Peg10 (paternally expressed gene 10) is an imprinted gene that is essential for placental development. It is thought to derive from a Ty3-gyspy LTR (long terminal repeat) retrotransposon and retains Gag and Pol-like domains. Here we show that the Gag domain of PEG10 can promote vesicle budding simil...

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Bibliographic Details
Main Authors: Mona Abed, Erik Verschueren, Hanna Budayeva, Peter Liu, Donald S Kirkpatrick, Rohit Reja, Sarah K Kummerfeld, Joshua D Webster, Sarah Gierke, Mike Reichelt, Keith R Anderson, Robert J Newman, Merone Roose-Girma, Zora Modrusan, Hazal Pektas, Emin Maltepe, Kim Newton, Vishva M Dixit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214110

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https://doi.org/10.1371/journal.pone.0214110

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