Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy

Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy

Abstract Background Sufentanil is commonly used for analgesia and sedation during extracorporeal membrane oxygenation (ECMO). Both ECMO and the pathophysiological changes derived from critical illness have significant effects on the pharmacokinetics (PK) of drugs, yet reports of ECMO and sufentanil...

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Bibliographic Details
Main Authors: Jongsung Hahn, Seungwon Yang, Kyoung Lok Min, Dasohm Kim, Byung Hak Jin, Changhun Park, Min Soo Park, Jin Wi, Min Jung Chang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Critical Care
Subjects:
Anaesthetics, intravenous
Sufentanil
Extracorporeal membrane oxygenation
Pharmacokinetics
Temperature
Online Access:http://link.springer.com/article/10.1186/s13054-019-2508-4

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http://link.springer.com/article/10.1186/s13054-019-2508-4

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