Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.

Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.

High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy. This highlights an urgent need to develop novel therapies and increase the efficacy of radio/chemotherapy for these very aggressive and malignant b...

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Bibliographic Details
Main Authors: Julie Sesen, Perrine Dahan, Sarah J Scotland, Estelle Saland, Van-Thi Dang, Anthony Lemarié, Betty M Tyler, Henry Brem, Christine Toulas, Elizabeth Cohen-Jonathan Moyal, Jean-Emmanuel Sarry, Nicolas Skuli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395104?pdf=render

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http://europepmc.org/articles/PMC4395104?pdf=render

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