RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.

Bibliographic Details
Main Authors: Megumi Shigematsu, Takuya Kawamura, Keisuke Morichika, Natsuko Izumi, Takashi Kiuchi, Shozo Honda, Venetia Pliatsika, Ryuma Matsubara, Isidore Rigoutsos, Susumu Katsuma, Yukihide Tomari, Yohei Kirino
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24681-w

Internet

https://doi.org/10.1038/s41467-021-24681-w

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