MicroRNA-3646 Contributes to Docetaxel Resistance in Human Breast Cancer Cells by GSK-3β/β-Catenin Signaling Pathway.

Acquisition of resistance to docetaxel (Doc) is one of the most important problems in treatment of breast cancer patients, but the underlying mechanisms are still not fully understood. In present study, Doc-resistant MDA-MB-231 and MCF-7 breast cancer cell lines (MDA-MB-231/Doc and MCF-7/Doc) were s...

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Bibliographic Details
Main Authors: Xiaohui Zhang, Shanliang Zhong, Yong Xu, Dandan Yu, Tengfei Ma, Lin Chen, Yang Zhao, Xiu Chen, Sujin Yang, Yueqin Wu, Jinhai Tang, Jianhua Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4821636?pdf=render