Effects of enriched environment on COX-2, leptin and eicosanoids in a mouse model of breast cancer.

Cyclooxygenase-2 (COX-2) and adipokines have been implicated in breast cancer. This study investigated a possible link between COX-2 and adipokines in the development of mammary tumors. A model of environmental enrichment (EE), known to reduce tumor growth was used for a syngeneic murine model of ma...

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Bibliographic Details
Main Authors: Rachida Nachat-Kappes, Alexandre Pinel, Kristell Combe, Bruno Lamas, Marie-Chantal Farges, Adrien Rossary, Nicolas Goncalves-Mendes, Florence Caldefie-Chezet, Marie-Paule Vasson, Samar Basu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3521763?pdf=render