Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China.

Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China.

Mitochondrial DNA (mtDNA) is particularly susceptible to oxidative damage and mutation due to the high rate of reactive oxygen species (ROS) production and limited DNA-repair capacity in mitochondrial. Previous studies demonstrated that the increased mtDNA copy number for compensation for damage, wh...

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Bibliographic Details
Main Authors: Shizhen Zheng, Pin Qian, Fuxiang Li, Guisheng Qian, Changzheng Wang, Guoming Wu, Qi Li, Yan Chen, Jin Li, Haining Li, Binfeng He, Fuyun Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283641?pdf=render

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http://europepmc.org/articles/PMC3283641?pdf=render

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