Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering

Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering

The human gyrovirus derived protein Apoptin (HGV-Apoptin) a homologue of the chicken anemia virus Apoptin (CAV-Apoptin), a protein with high cancer cells selective toxicity, triggers apoptosis selectively in cancer cells. In this paper, we show that HGV-Apoptin acts independently from the death rec...

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Bibliographic Details
Main Authors: Wiem Chaabane, Artur Cieślar-Pobuda, Mohamed El-Gazzah, Mayur V. Jain, Joanna Rzeszowska-Wolny, Mehrdad Rafat, Joerg Stetefeld, Saeid Ghavami, Marek J. Łos
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614001079

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http://www.sciencedirect.com/science/article/pii/S1476558614001079

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