Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification

During spinal cord development, Sonic hedgehog (Shh), secreted from the floor plate, plays an important role in the production of motor neurons by patterning the ventral neural tube, which establishes MN progenitor identity. It remains unknown, however, if Shh signaling plays a role in generating co...

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Bibliographic Details
Main Authors: Heejin Nam, Shin Jeon, Hyejin An, Jaeyoung Yoo, Hyo-Jong Lee, Soo-Kyung Lee, Seunghee Lee
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/46683