Depletion of ATP Limits Membrane Excitability of Skeletal Muscle by Increasing Both ClC1-Open Probability and Membrane Conductance

Depletion of ATP Limits Membrane Excitability of Skeletal Muscle by Increasing Both ClC1-Open Probability and Membrane Conductance

Activation of skeletal muscle contractions require that action potentials can be excited and propagated along the muscle fibers. Recent studies have revealed that muscle fiber excitability is regulated during repeated firing of action potentials by cellular signaling systems that control the functio...

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Bibliographic Details
Main Authors: Pieter Arnold Leermakers, Kamilla Løhde Tordrup Dybdahl, Kristian Søborg Husted, Anders Riisager, Frank Vincenzo de Paoli, Tomàs Pinós, John Vissing, Thomas Oliver Brøgger Krag, Thomas Holm Pedersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
skeletal muscle
ATP
membrane excitability
fatigue
membrane conductance
ClC-1
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00541/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00541/full

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