An efficient algorithm for systematic analysis of nucleotide strings suitable for siRNA design

<p>Abstract</p> <p>Background</p> <p>The "off-target" silencing effect hinders the development of siRNA-based therapeutic and research applications. Existing solutions for finding possible locations of siRNA seats within a large database of genes are either to...

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Bibliographic Details
Main Authors: Bode Jonathan, Baranova Ancha, Manyam Ganiraju, Emelianenko Maria
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/4/168