Systemic and Oral Immunogenicity of Porcine Epidemic Diarrhea Virus Antigen Fused to Poly-Fc of Immunoglobulin G and Expressed in ΔXT/FT Nicotiana benthamiana Plants

Systemic and Oral Immunogenicity of Porcine Epidemic Diarrhea Virus Antigen Fused to Poly-Fc of Immunoglobulin G and Expressed in ΔXT/FT Nicotiana benthamiana Plants

Porcine epidemic diarrhea virus (PEDV), a member of the Coronaviridae family has become increasingly probelmatic in the pig farming industry. Currently, there are no effective, globally applicable vaccines against PEDV. Here, we tested a recombinant PEDV vaccine candidate based on the expression of...

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Bibliographic Details
Main Authors: Nguyen-Quang-Duc Tien, Moon-Sik Yang, Yong-Suk Jang, Tae-Ho Kwon, Rajko Reljic, Mi-young Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
vaccine
PEDV
mucosal
immunity
plant
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.653064/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.653064/full

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