ESI–LC–MS/MS for Therapeutic Drug Monitoring of Binary Mixture of Pregabalin and Tramadol: Human Plasma and Urine Applications

ESI–LC–MS/MS for Therapeutic Drug Monitoring of Binary Mixture of Pregabalin and Tramadol: Human Plasma and Urine Applications

Tramadol (TRM) and pregabalin (PGB) are frequently used in combination for neuropathic pain management. Accordingly, a selective and sensitive high-performance liquid chromatography–electrospray ionization–mass/mass spectrometric (ESI–LC–MS/MS) method is presented for determination of TRM and PGB, w...

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Bibliographic Details
Main Authors: Atiah H. Almalki, Nesma A. Ali, Fadwa A. Elroby, Mohamed R. El Ghobashy, Aml A. Emam, Ibrahim A. Naguib
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Separations
Subjects:
pregabalin
tramadol
neuropathic pain
ESI–LC–MS/MS
therapeutic drug monitoring
Online Access:https://www.mdpi.com/2297-8739/8/2/21

Internet

https://www.mdpi.com/2297-8739/8/2/21

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