Inducible nitric oxide inhibitors block NMDA antagonist-stimulated motoric behaviors and medial prefrontal cortical glutamate efflux

Nitric oxide (NO) plays a critical role in the motoric and glutamate releasing action of N-methyl-D-aspartate (NMDA)-antagonist stimulants. Earlier studies utilized neuronal nitric oxide synthase inhibitors (nNOS) for studying the neurobehavioral effects of noncompetitive NMDA-antagonist stimulants...

Full description

Bibliographic Details
Main Authors: Hadley C Bergstrom, Altaf eDavesh, S Paul Berger
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00292/full