ROS and Sympathetically mediated Mitochondria activation in Brown Adipose Tissue contributes to Methamphetamine-induced hyperthermia

ROS and Sympathetically mediated Mitochondria activation in Brown Adipose Tissue contributes to Methamphetamine-induced hyperthermia

Methamphetamine abuse has been shown to induce alterations in mitochondrial function in the brain as well as to induce hyperthermia, which contributes to neurotoxicity and Meth-associated mortality. Brown adipose tissue (BAT), a thermogenic site known to be important in neonates, has recently regain...

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Bibliographic Details
Main Authors: Manuel eSanchez-Alavez, Bruno eConti, Malcolm Robert Wood, Nikki eBortell, Eduardo Alejandro Bustamante, Enrique eSaez, Howard S Fox, Maria Cecilia G Marcondes
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Endocrinology
Subjects:
Methamphetamine
Mitochondria
Thermogenesis
hyperthermia
brown adipose tissue
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00044/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00044/full

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