Human tissue cultures of lung cancer predict patient susceptibility to immune-checkpoint inhibition

Abstract Despite novel immunotherapies being approved and established for the treatment of non-small cell lung cancer (NSCLC), ex vivo models predicting individual patients’ responses to immunotherapies are missing. Especially immune modulating therapies with moderate response rates urge for biomark...

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Bibliographic Details
Main Authors: David Junk, Sebastian Krämer, Johannes Broschewitz, Hennig Laura, Chiara Massa, Yousef Moulla, Ngoc Anh Hoang, Astrid Monecke, Uwe Eichfeld, Ingo Bechmann, Florian Lordick, Barbara Seliger, Sonja Kallendrusch
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00651-5