Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice.

OBJECTIVES:We previously found that elevated energy expenditure following a single oral dose of flavan 3-ols (FL), a mixture of catechins and B type procyanidins, is caused by sympathetic nerve activation. In the present study, we compared the activity of the FL components (-)-epicatechin (EC; monom...

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Main Authors: Yuta Nakagawa, Kana Ishimura, Satomi Oya, Masaki Kamino, Yasuyuki Fujii, Fumio Nanba, Toshiya Toda, Takeshi Ishii, Takahiro Adachi, Yoshitomo Suhara, Naomi Osakabe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6066223?pdf=render