Detecting disease-associated genomic outcomes using constrained mixture of Bayesian hierarchical models for paired data.

Detecting disease-associated genomic outcomes is one of the key steps in precision medicine research. Cutting-edge high-throughput technologies enable researchers to unbiasedly test if genomic outcomes are associated with disease of interest. However, these technologies also include the challenges a...

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Bibliographic Details
Main Authors: Yunfeng Li, Jarrett Morrow, Benjamin Raby, Kelan Tantisira, Scott T Weiss, Wei Huang, Weiliang Qiu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5373614?pdf=render