Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival

Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival

Current routine cell culture techniques are only poorly suited to capture the physiological complexity of tumor microenvironments, wherein tumor cell function is affected by intricate three-dimensional (3D), integrin-dependent cell-cell and cell-extracellular matrix (ECM) interactions. 3D cell cultu...

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Bibliographic Details
Main Authors: Dietmar W. Hutmacher, Matthias P. Lutolf, Daniela Loessner, Judith A. Clements, Stefan Kobel
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Microarrays
Subjects:
microwell arrays
cell aggregates
bioengineered microenvironments
ovarian cancer
kallikreins
integrins
paclitaxel
Online Access:http://www.mdpi.com/2076-3905/2/3/208

Internet

http://www.mdpi.com/2076-3905/2/3/208

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