Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-deficient Mice: Role of NOX4/NF-κB Mediated Lectin-like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium

Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-deficient Mice: Role of NOX4/NF-κB Mediated Lectin-like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium

Dihydrotanshinone I (DHT) is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. However, its role in atherosclerosis remains unclear. In this study, the effect of DHT on atherosclerosis were investigated using apolipoprotein E...

Full description

Bibliographic Details
Main Authors: Wenwen Zhao, Chunxia Li, Hongwei Gao, Qin Wu, Jingshan Shi, Xiuping Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
Atherosclerosis
Reactive Oxygen Species
lipopolysaccharide
LOX-1
Dihydrotanshinone I
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00418/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00418/full

Similar Items