Metabolomic Analysis of Plasma from <i>GABA<sub>B(1)</sub></i> Knock-Out Mice Reveals Decreased Levels of Elaidic <i>Trans</i>-Fatty Acid

Metabolomic Analysis of Plasma from <i>GABA<sub>B(1)</sub></i> Knock-Out Mice Reveals Decreased Levels of Elaidic <i>Trans</i>-Fatty Acid

Mice lacking the GABA<sub>B(1)</sub> subunit of gamma-aminobutyric acid (GABA) type B receptors exhibit spontaneous seizures, hyperalgesia, hyperlocomotor activity, and memory impairment. Although mice lacking the GABA<sub>B(1)</sub> subunit are viable, they are sterile, and...

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Bibliographic Details
Main Authors: Claudia Fattuoni, Luigi Barberini, Antonio Noto, Paolo Follesa
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Metabolites
Subjects:
murine model
plasma
metabolomics
GC-MS
elaidic acid
Online Access:https://www.mdpi.com/2218-1989/10/12/484

Internet

https://www.mdpi.com/2218-1989/10/12/484

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