HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors.

HAMP domains are signal relay modules in >26,000 receptors of bacteria, eukaryotes, and archaea that mediate processes involved in chemotaxis, pathogenesis, and biofilm formation. We identify two HAMP conformations distinguished by a four- to two-helix packing transition at the C-termini that sen...

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Bibliographic Details
Main Authors: Michael V Airola, Nattakan Sukomon, Dipanjan Samanta, Peter P Borbat, Jack H Freed, Kylie J Watts, Brian R Crane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3570549?pdf=render