Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition

Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition

This study aimed to utilize cholesterol conjugation of 5-fluorouracil (5-FUC) and liposomal formulas to enhance the partitioning of 5-FU into low density lipoprotein (LDL) to target hepatocellular carcinoma (HCC). Thus, 5-FU and 5-FUCwere loaded into liposomes. Later, the direct loading and transfer...

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Bibliographic Details
Main Authors: Saleh A. Alanazi, Gamaleldin I. Harisa, Mohamed M. Badran, Fars K. Alanazi, Ehab Elzayat, Abdullah H. Alomrani, Osaid T. Al Meanazel, Ahmed T. Al Meanazel
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
5-fluorouracil
5-fuc
liposomes
cytotoxicity
ldl
liver targeting
Online Access:http://dx.doi.org/10.1080/21655979.2021.1896202

Internet

http://dx.doi.org/10.1080/21655979.2021.1896202

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