Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway

Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway

Parasitic helminths infect over a billion humans. To survive in the low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — this requires rhodoquinone (RQ), an electron carrier that is made by very few animal species. Crucially RQ is not made or used by any parasiti...

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Bibliographic Details
Main Authors: Samantha Del Borrello, Margot Lautens, Kathleen Dolan, June H Tan, Taylor Davie, Michael R Schertzberg, Mark A Spensley, Amy A Caudy, Andrew G Fraser
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
anaerobic metabolism
rhodoquinone
parasitic helminth
global health
Online Access:https://elifesciences.org/articles/48165

Internet

https://elifesciences.org/articles/48165

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