NLRP3 and CARD8 polymorphisms influence higher disease activity in rheumatoid arthritis

Background: The activation of NLRP3-inflammasome may contribute to inflammatory processes in rheumatoid arthritis (RA). Functional polymorphisms in the genes coding for its components NLRP3 and CARD8 were associated with a proinflammatory phenotype. Our aim was to investigate the influence of these...

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Bibliographic Details
Main Authors: Jenko Barbara, Praprotnik Sonja, Tomšić Matija, Dolžan Vita
Format: Article
Language:English
Published: Society of Medical Biochemists of Serbia, Belgrade 2016-01-01
Series:Journal of Medical Biochemistry
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2016/1452-82581603319J.pdf