A synthetic peptide sensitizes multi-drug resistant Pseudomonas aeruginosa to antibiotics for more than two hours and permeabilizes its envelope for twenty hours

Abstract Background Pseudomonas aeruginosa is a Gram-negative pathogen that frequently causes life-threatening infections in immunocompromised patients. We previously showed that subinhibitory concentrations of short synthetic peptides permeabilize P. aeruginosa and enhance the lethal action of co-a...

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Bibliographic Details
Main Authors: Iosu Rázquin-Olazarán, Hawraa Shahrour, Guillermo Martínez-de-Tejada
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-020-00678-3