Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.

Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.

Flawed ABC transporter functions may contribute to increased risk of drug-induced liver injury (DILI). We aimed to analyse the influence of genetic variations in ABC transporters on the risk of DILI development and clinical presentations in a large Spanish DILI cohort.A total of ten polymorphisms in...

Full description

Bibliographic Details
Main Authors: Eugenia Ulzurrun, Camilla Stephens, Francisco Ruiz-Cabello, Mercedes Robles-Diaz, Pablo Saenz-López, Hacibe Hallal, German Soriano, Eva Roman, M Carmen Fernandez, M Isabel Lucena, Raúl J Andrade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986086?pdf=render

Internet

http://europepmc.org/articles/PMC3986086?pdf=render

Similar Items