Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity

Type I interferons (IFNs) were first described for their ability to protect the host from viral infections and may also have beneficial effects under specific conditions within some bacterial infections. Yet, these pleiotropic cytokines are now known to exacerbate infections by numerous life-threate...

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Bibliographic Details
Main Authors: Laurel L Lenz, Emily M Eshleman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00431/full