A Simple, Rapid and Mild One Pot Synthesis of Benzene Ring Acylated and Demethylated Analogues of Harmine under Solvent-free Conditions

A Simple, Rapid and Mild One Pot Synthesis of Benzene Ring Acylated and Demethylated Analogues of Harmine under Solvent-free Conditions

A simple, rapid, solvent-free, room temperature one pot synthesis of benzene ring acylated and demethylated analogues of harmine using acyl halides/acid anhydrides and AlCl3 has been developed. Eight different acyl halides/acid anhydrides were used in the synthesis. The resulting mixture of products...

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Bibliographic Details
Main Authors: Bina S. Siddiqui, Syed Imran Hassan, Farhat Farhat, Syed Nawazish Ali, Sabira Begum
Format: Article
Language:English
Published: MDPI AG 2008-08-01
Series:Molecules
Subjects:
Solvent-free reactions
Friedel-Crafts acylation
β-carboline
harmine
acylharmine
demethylation.
Online Access:http://www.mdpi.com/1420-3049/13/8/1584/

Internet

http://www.mdpi.com/1420-3049/13/8/1584/

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