Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers

Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N–terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.

Bibliographic Details
Main Authors:	Rosario González-Muñiz, Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Fernando Albericio, Laura Zaccaro, Miriam Royo, Mª Teresa García-López, Mª Jesús Pérez de Vega
Format:	Article
Language:	English
Published:	MDPI AG 2010-07-01
Series:	Molecules
Subjects:	solid-phase Trp(Nps) dipeptides TRPV1 channel blockers
Online Access:	http://www.mdpi.com/1420-3049/15/7/4924/

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spelling	doaj-93fb60875f7140c5808ab0f070b3fc652020-11-24T21:08:08ZengMDPI AGMolecules1420-30492010-07-011574924493310.3390/molecules15074924Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel BlockersRosario González-MuñizAntonio Ferrer-MontielAsia Fernández-CarvajalFernando AlbericioLaura ZaccaroMiriam RoyoMª Teresa García-LópezMª Jesús Pérez de VegaTrp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N–terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists. http://www.mdpi.com/1420-3049/15/7/4924/solid-phaseTrp(Nps) dipeptidesTRPV1 channel blockers
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Rosario González-Muñiz Antonio Ferrer-Montiel Asia Fernández-Carvajal Fernando Albericio Laura Zaccaro Miriam Royo Mª Teresa García-López Mª Jesús Pérez de Vega
spellingShingle	Rosario González-Muñiz Antonio Ferrer-Montiel Asia Fernández-Carvajal Fernando Albericio Laura Zaccaro Miriam Royo Mª Teresa García-López Mª Jesús Pérez de Vega Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers Molecules solid-phase Trp(Nps) dipeptides TRPV1 channel blockers
author_facet	Rosario González-Muñiz Antonio Ferrer-Montiel Asia Fernández-Carvajal Fernando Albericio Laura Zaccaro Miriam Royo Mª Teresa García-López Mª Jesús Pérez de Vega
author_sort	Rosario González-Muñiz
title	Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers
title_short	Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers
title_full	Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers
title_fullStr	Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers
title_full_unstemmed	Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers
title_sort	solid-phase synthesis of new trp(nps)-containing dipeptide derivatives as trpv1 channel blockers
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2010-07-01
description	Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N–terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.
topic	solid-phase Trp(Nps) dipeptides TRPV1 channel blockers
url	http://www.mdpi.com/1420-3049/15/7/4924/
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Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers

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