Cost analysis based on bioreactor cultivation conditions: Production of a soluble recombinant protein using Escherichia coli BL21(DE3)

Cost analysis based on bioreactor cultivation conditions: Production of a soluble recombinant protein using Escherichia coli BL21(DE3)

The impact of cultivation strategy on the cost of recombinant protein production is crucial for defining cost-effective bioreactor operation conditions. This paper presents a methodology to estimate and compare cost impacts related to utilities as well as medium composition, using simple design equa...

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Bibliographic Details
Main Authors: Valdemir M. Cardoso, Gilson Campani, Maurício P. Santos, Gabriel G. Silva, Manuella C. Pires, Viviane M. Gonçalves, Roberto de C. Giordano, Cíntia R. Sargo, Antônio C.L. Horta, Teresa C. Zangirolami
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biotechnology Reports
Subjects:
Batch culture
Energy consumption
Process economic analysis
Stirred-Tank reactor
Bioprocess engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X1930637X

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http://www.sciencedirect.com/science/article/pii/S2215017X1930637X

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