The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients

The interaction of major histocompatibility complex class I chain-related protein A (MICA) and its cognate activating receptor natural killer (NK) group 2 member D (NKG2D) receptor plays a significant role in viral immune control. In the context of kidney transplantation (KTx), cytomegalovirus (CMV)...

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Main Authors: Hana Rohn, Rafael Tomoya Michita, Esther Schwich, Sebastian Dolff, Anja Gäckler, Mirko Trilling, Vu Thuy Khanh Le-Trilling, Benjamin Wilde, Johannes Korth, Falko M. Heinemann, Peter A. Horn, Andreas Kribben, Oliver Witzke, Vera Rebmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
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Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00917/full