Detection of methylated SEPT9 in plasma is a reliable screening method for both left- and right-sided colon cancers.

BACKGROUND:Methylated Septin 9 (SEPT9) is a sensitive biomarker for colorectal cancer (CRC) from peripheral blood. However, its relationship to cancer localization, guaiac-based fecal occult blood test (gFOBT) and carcinoembryonic antigen (CEA) have not been described. METHODOLOGY/PRINCIPAL FINDINGS...

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Main Authors: Kinga Tóth, Ferenc Sipos, Alexandra Kalmár, Arpád V Patai, Barnabás Wichmann, Robert Stoehr, Henriette Golcher, Vera Schellerer, Zsolt Tulassay, Béla Molnár
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457959?pdf=render