Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

Genetic recombination contributes to the diversity of human immunodeficiency virus (HIV-1). Productive HIV-1 recombination is, however, dependent on both the number of HIV-1 genomes per infected cell and the genetic relationship between these viral genomes. A detailed analysis of the number of provi...

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Bibliographic Details
Main Authors: Lina Josefsson, Sarah Palmer, Nuno R Faria, Philippe Lemey, Joseph Casazza, David Ambrozak, Mary Kearney, Wei Shao, Shyamasundaran Kottilil, Michael Sneller, John Mellors, John M Coffin, Frank Maldarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23818847/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23818847/?tool=EBI

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