Role of NLRs in the Regulation of Type I Interferon Signaling, Host Defense and Tolerance to Inflammation

Role of NLRs in the Regulation of Type I Interferon Signaling, Host Defense and Tolerance to Inflammation

Type I interferon signaling contributes to the development of innate and adaptive immune responses to either viruses, fungi, or bacteria. However, amplitude and timing of the interferon response is of utmost importance for preventing an underwhelming outcome, or tissue damage. While several pathogen...

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Bibliographic Details
Main Authors: Ioannis Kienes, Tanja Weidl, Nora Mirza, Mathias Chamaillard, Thomas A. Kufer
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
NOD-like receptors
Interferons
innate immunity
immune regulation
type I interferon
antiviral
Online Access:https://www.mdpi.com/1422-0067/22/3/1301

Internet

https://www.mdpi.com/1422-0067/22/3/1301

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