Intra-articular injection of an antioxidant formulation did not improve structural degeneration in a rat model of post-traumatic osteoarthritis

Intra-articular injection of an antioxidant formulation did not improve structural degeneration in a rat model of post-traumatic osteoarthritis

Background/objective: Oxidative stress plays an important role in osteoarthritis (OA), causing inflammation and matrix degradation in joints. Previous studies have shown that antioxidants such as quercetin and vitamin C are potential candidates for treating OA. We aimed to determine whether a formul...

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Bibliographic Details
Main Authors: Yau-Chuk Cheuk, Sai-Chuen Fu, Sze-Wing Mok, Kevin Ki-Wai Ho, Leung-Kim Hung, Kai-Ming Chan
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Orthopaedic Translation
Subjects:
antioxidant
deferoxamine
osteoarthritis
oxidative stress
quercetin
vitamin C
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X16302583

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http://www.sciencedirect.com/science/article/pii/S2214031X16302583

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