Small Molecule-Induced Complement Factor D (Adipsin) Promotes Lipid Accumulation and Adipocyte Differentiation.

Adipocytes are differentiated by various transcriptional cascades integrated on the master regulator, Pparγ. To discover new genes involved in adipocyte differentiation, preadipocytes were treated with three newly identified pro-adipogenic small molecules and GW7845 (a Pparγ agonist) for 24 hours an...

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Bibliographic Details
Main Authors: No-Joon Song, Suji Kim, Byung-Hyun Jang, Seo-Hyuk Chang, Ui Jeong Yun, Ki-Moon Park, Hironori Waki, Dean Y Li, Peter Tontonoz, Kye Won Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017651?pdf=render