AMP-activated protein kinase activation ameliorates eicosanoid dysregulation in high-fat-induced kidney disease in mice

High-fat diet (HFD) causes renal lipotoxicity that is ameliorated with AMP-activated protein kinase (AMPK) activation. Although bioactive eicosanoids increase with HFD and are essential in regulation of renal disease, their role in the inflammatory response to HFD-induced kidney disease and their mo...

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Bibliographic Details
Main Authors: Anne-Emilie Declèves, Anna V. Mathew, Aaron M. Armando, Xianlin Han, Edward A. Dennis, Oswald Quehenberger, Kumar Sharma
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322641