Pioglitazone ameliorates retinal ischemia/reperfusion injury via suppressing NLRP3 inflammasome activities

AIM: To explore the role of Pioglitazone (Pio) on a mouse model of retinal ischemia/reperfusion (I/R) injury and to elucidate the potential mechanism. METHODS: Retinal ischemia was induced in mice by increasing the intraocular pressure, and Pio was administered 4h though periocular injection before...

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Bibliographic Details
Main Authors: Yue-Lu Zhang, Ruo-Bing Wang, Wei-Yi Li, Fang-Zhou Xia, Lin Liu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-12-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2017/12/20171204.pdf