Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1.

Mitochondrial shape is determined by fission and fusion reactions catalyzed by large GTPases of the dynamin family, mutation of which can cause neurological dysfunction. While fission-inducing protein phosphatases have been identified, the identity of opposing kinase signaling complexes has remained...

Full description

Bibliographic Details
Main Authors: Ronald A Merrill, Ruben K Dagda, Audrey S Dickey, J Thomas Cribbs, Steven H Green, Yuriy M Usachev, Stefan Strack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21526220/?tool=EBI