Syntenin controls migration, growth, proliferation and cell cycle progression in cancer cells.

Syntenin controls migration, growth, proliferation and cell cycle progression in cancer cells.

The scaffold protein syntenin abounds during fetal life where it is important for developmental movements. In human adulthood, syntenin gain-of-function is increasingly associated with various cancers and poor prognosis. Depending on the cancer model analyzed, syntenin affects various signaling path...

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Bibliographic Details
Main Authors: Rudra eKashyap, Bart eRoucourt, Frederique eLembo, Joanna eFares, Ane eMarcos-Carcavilla, Audrey eRestouin, Pascale eZimmermann, Rania eGhossoub
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Pharmacology
Subjects:
Cell Cycle
Syndecans
Cancer cell migration
Cancer cell growth
Syntenin
PDZ proteins
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00241/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00241/full

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