Grafted Human iPSC-Derived Neural Progenitor Cells Express Integrins and Extend Long-Distance Axons Within the Developing Corticospinal Tract

Grafted Human iPSC-Derived Neural Progenitor Cells Express Integrins and Extend Long-Distance Axons Within the Developing Corticospinal Tract

After spinal cord injury (SCI), regeneration of adult motor axons such as axons in the corticospinal tract (CST) is severely limited. Alongside the inhibitory lesion environment, most neuronal subtypes in the mature central nervous system (CNS) are intrinsically unrepairable. With age, expression of...

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Bibliographic Details
Main Authors: Lindsey H. Forbes, Melissa R. Andrews
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
α9 integrin
induced pluripotent stem cell
transplantation
neural progenitor cell
sensorimotor cortex
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00026/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00026/full

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