Estrogen promotes the onset and development of idiopathic scoliosis via disproportionate endochondral ossification of the anterior and posterior column in a bipedal rat model

Orthopedics: Staying ahead of the curve Treatments that reduce estrogen levels may prevent the development of spinal curvature associated with adolescent idiopathic scoliosis, curvature of the spine. Estrogen has been linked to scoliosis in the past, but the nature of this relationship remains contr...

Full description

Bibliographic Details
Main Authors: Shuhui Zheng, Hang Zhou, Bo Gao, Yongyong Li, Zhiheng Liao, Taifeng Zhou, Chengjie Lian, Zizhao Wu, Deying Su, Tingting Wang, Peiqiang Su, Caixia Xu
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0161-7