Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization
Summary: Generating robust CD4+ T-helper cell type 1 (Th1) responses is essential for protective vaccine-induced type 1 immunity. Here, we examine whether immunization formulation associated with enhanced vaccine efficacy promotes antigen targeting and cell recruitment into lymph node (LN) niches as...
Main Authors: | Jeffrey Lian, Aleksandra J. Ozga, Caroline L. Sokol, Andrew D. Luster |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112472030632X |
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