Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degenerationResearch in context

Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degenerationResearch in context

Background: We have previously reported that xeno-transplanted human ESC-derived retinas are able to mature in the immunodeficient retinal degeneration rodent models, similar to allo-transplantations using mouse iPSC-derived retina. The photoreceptors in the latter developed outer segments and forme...

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Bibliographic Details
Main Authors: Hung-Ya Tu, Takehito Watanabe, Hiroshi Shirai, Suguru Yamasaki, Masaharu Kinoshita, Keizo Matsushita, Tomoyo Hashiguchi, Hirotaka Onoe, Take Matsuyama, Atsushi Kuwahara, Akiyoshi Kishino, Toru Kimura, Mototsugu Eiraku, Kiyoshi Suzuma, Takashi Kitaoka, Masayo Takahashi, Michiko Mandai
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305322

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http://www.sciencedirect.com/science/article/pii/S2352396418305322

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