Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis.

Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis.

Dendritic cells (DCs) are professional antigen presenting cells that have the dual ability to stimulate immunity and maintain tolerance. However, the signalling pathways mediating tolerogenic DC function in vivo remain largely unknown. The β-catenin pathway has been suggested to promote a regulatory...

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Bibliographic Details
Main Authors: C Henrique Alves, Julia L Ober-Blöbaum, Inge Brouwers-Haspels, Patrick S Asmawidjaja, Adriana M C Mus, Wida Razawy, Marlieke Molendijk, Björn E Clausen, Erik Lubberts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4654567?pdf=render

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http://europepmc.org/articles/PMC4654567?pdf=render

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