Triptolide Induces Apoptosis Through Fas Death and Mitochondrial Pathways in HepaRG Cell Line

Triptolide isolated from the traditional Chinese herb Tripterygium wilfordii Hook F., possesses anti-tumor, anti-fertility, and anti-inflammatory properties. Triptolide-induced hepatotoxicity has continued to engage the attention of researchers. However, not much is yet known about the cytotoxicity...

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Bibliographic Details
Main Authors: Longtai You, Xiaoxv Dong, Boran Ni, Jing Fu, Chunjing Yang, Xingbin Yin, Xin Leng, Jian Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
ROS
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00813/full