ReSeq simulates realistic Illumina high-throughput sequencing data

Abstract In high-throughput sequencing data, performance comparisons between computational tools are essential for making informed decisions at each step of a project. Simulations are a critical part of method comparisons, but for standard Illumina sequencing of genomic DNA, they are often oversimpl...

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Bibliographic Details
Main Authors: Stephan Schmeing, Mark D. Robinson
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02265-7