Delay Differential Model for Tumour-Immune Response with Chemoimmunotherapy and Optimal Control

We present a delay differential model with optimal control that describes the interactions of the tumour cells and immune response cells with external therapy. The intracellular delay is incorporated into the model to justify the time required to stimulate the effector cells. The optimal control var...

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Bibliographic Details
Main Authors: F. A. Rihan, D. H. Abdelrahman, F. Al-Maskari, F. Ibrahim, M. A. Abdeen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2014/982978