Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS

Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS

Previous studies have revealed the anti-inflammatory and neuroprotective properties of <i>Hericium erinaceus</i> extracts, including the fact that the active ingredient erinacine C (EC) can induce the synthesis of nerve growth factor. However, there is limited research on the use and mec...

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Bibliographic Details
Main Authors: Li-Yu Wang, Chin-Shiu Huang, Yu-Hsuan Chen, Chin-Chu Chen, Chien-Chih Chen, Cheng-Hung Chuang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
neuroinflammation
microglial cells
nitric oxide
erinacine C
proinflammatory cytokines
<i>Hericium erinaceus</i> mycelium
Online Access:https://www.mdpi.com/1420-3049/24/18/3317

Internet

https://www.mdpi.com/1420-3049/24/18/3317

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